ASSISTANT PROFESSOR IN PHARMACOLOGY – NCA – CAT NO 150/2018 – MEDICAL EDUCATION

FINAL ANSWER KEY
Question Paper Code: 21/2019/OL
Category Code: 150/2018
Exam: Assistant Professor Pharmacology NCA
Medium of Question: English
Date of Test :19-06-2019
Department :Medical Education
Alphacode :A
Question1:-The pass that connects Himachal Pradesh and Tibet is
A:-Shipkila
B:-Nathula
C:-Banihal
D:-Sojila
Correct Answer:- Option-A
Question2:-Name the chief Justice who issued verdict on the constitutionality of Adhar Card
A:-T.S. Thakkur
B:-Ranjan Gagoi
C:-Dipak Misra
D:-None of these
Correct Answer:- Option-C
Question3:-The founder of East India Association was
A:-Surendra Nath Banerjee
B:-Mahadev G. Ranade
C:-Gopala Krishna Gokhale
D:-Dadabai Naorji
Correct Answer:- Option-D
Question4:-Among the rivers given below which one flows to west?
A:-Kaveri
B:-Godavari
C:-Mahanadi
D:-Narmada
Correct Answer:- Option-D
Question5:-Dassault Aviation is an aircraft company from
A:-Korea
B:-Italy
C:-America
D:-France
Correct Answer:- Option-D
Question6:-In which annual session of Indian National Congress was, C. Sankaran Nair elected as the PresidA:-Bombay Session
B:-Madras Session
C:-Amaravathi Session
D:-Nagpur Session
Correct Answer:- Option-C
Question7:-Mar Kuriakose Elias Chavara established a Sanskrit school at
A:-Kollam
B:-Mannanam
C:-Kaladi
D:-Aluva
Correct Answer:- Option-B
Question8:-The 44th G.7 summit was held at
A:-Berlin
B:-Tokyo
C:-Melbaie
D:-Paris
Correct Answer:- Option-C
Question9:-The constitutional reform that introduced dyarchy in provinces was
A:-Minto Morly Reforms
B:-Indian Act of 1935
C:-Montagu Chelmsford Reform
D:-Indian act of 1858
Correct Answer:- Option-C
Question10:-The revolt of Royal Indian Navy in 1946 begin in
A:-Karachi
B:-Vishakhapatanam
C:-Bombay
D:-Kolkata
Correct Answer:- Option-C
Question11:-Tata Iron and Steel Plant (TISCO) is situated at
A:-Jharkand
B:-West Bengal
C:-Karnataka
D:-Bihar
Correct Answer:- Option-A
Question12:-‘Prachina Malayalam’ is the work of
A:-Vaghbhadanandha
B:-Vaikunda Swamikal
C:-V.T. Bhattathirippad
D:-Chattampi Swamikal
Correct Answer:- Option-D
Question13:-The venue of 2022 World Cup Foot Ball is
A:-Russia
B:-Mexico
C:-Qatar
D:-Canada
Correct Answer:- Option-C
Question14:-As per 2011 Census Report the district with highest sex ratio is
A:-Malappuram
B:-Alappuzha
C:-Kannur
D:-Thiruvananthapuram
Correct Answer:- Option-C
Question15:-‘Mangalavanam’ bird sanctuary is in
A:-Palakkad
B:-Idukki
C:-Kottayam
D:-Ernakulam
Correct Answer:- Option-D
Question16:-The district with longest coastal area is
A:-Kasargod
B:-Kozhikode
C:-Alappuzha
D:-Kannur
Correct Answer:- Option-D
Question17:-Edamalayar Dam is constructed upon the river
A:-Periyar
B:-Pampa
C:-Neyyar
D:-Bharathapuzha
Correct Answer:- Option-A
Question18:-Mahatma Gandhi National Rural Employment Guarantee Programme (MNREGP) was introducedA:-2005
B:-2004
C:-2008
D:-2006
Correct Answer:- Option-A
Question19:-‘Ezhava Memorial’ was submitted to
A:-Sree Chithira Thirunal Balarama Varma
B:-Gouri Parvathi Bhai
C:-Sree Moolam Thirunal Ramavarma
D:-Visakham Thirunal
Correct Answer:- Option-C
Question20:-‘Yachanayatra’ was conducted by
A:-A.K. Gopalan
B:-T.K. Madhavan
C:-V.T. Bhattathirippad
D:-K. Kelappan
Correct Answer:- Option-C
Question21:-Domperidone is
A:- antagonist
B:- agonist
C:-D2 antagonist
D:-D2 agonist
Correct Answer:- Option-C
Question22:-Drug of choice in neurocysticercosis
A:-Praziquantel
B:-Albendazole
C:-Ivermectin
D:-Pyrantal pamoate
Correct Answer:- Option-B
Question23:-Stiripentol is an
A:-Antipsychotic
B:-Antiepileptic
C:-Antiparkinsonian
D:-Antidepressant
Correct Answer:- Option-B
Question24:-All are catecholamines except
A:-Epinephrine
B:-Norepinephrine
C:-Dopamine
D:-Phenylephrine
Correct Answer:- Option-D
Question25:-Fastest acting antimalarial drug
A:-Chloroquine
B:-Quinine
C:-Mefloquine
D:-Artesunate
Correct Answer:- Option-D
Question26:-The mechanism of action of sofosbuvir is
A:-NS5B polymerase inhibitor
B:-NS5A inhibitor
C:-NS3 Protease inhibitor
D:-Neuraminidase inhibitor
Correct Answer:- Option-A
Question27:-Drug which is not of microbial origin
A:-Lovastatin
B:-Ivermectin
C:-Paclitaxel
D:-Sirolimus
Correct Answer:- Option-C
Question28:-Essential drugs are
A:-Life saving drugs
B:-Drugs meeting the health needs of majority of population
C:-Drugs that must be available in emergency departments
D:-Drugs that are listed in pharmacopoeia of a nation
Correct Answer:- Option-B
Question29:-Loading dose of a drug primarily depends on
A:-Volume of distribution
B:-Clearance
C:-Rate of administration
D:-Plasma half-life
Correct Answer:- Option-A
Question30:-Selective estrogen receptor down regulator is
A:-Clomiphene citrate
B:-Toremifene
C:-Letrozole
D:-Fulvestrant
Correct Answer:- Option-D
Question31:-Ocular anti inflammatory agent among the following
A:-Flurbiprofen
B:-Indomethacin
C:-Mefenamic acid
D:-Piroxicam
Correct Answer:- Option-A
Question32:-NMDA receptor antagonist useful in Alzheimer’s disease
A:-Galantamine
B:-Memantine
C:-Donepezil
D:-Co Dergocrine
Correct Answer:- Option-B
Question33:-Uses of ACE inhibitors are all except
A:-Hypertension
B:-Congestive cardiac failure
C:-Myocardial infarction
D:-Variant angina
Correct Answer:- Option-D
Question34:-Teriparatide can be used for the treatment of
A:-Osteoporosis
B:-Polycystic ovarian disease
C:-Hyperparathyroidism
D:-Hypocalcemia
Correct Answer:- Option-A
Question35:-Drug of choice in trigeminal neuralgia
A:-Carbamazepine
B:-Phenytoin
C:-Lamotrigine
D:-Sodium valproate
Correct Answer:- Option-A
Question36:-Conversion of T4 to T3 is inhibited by all EXCEPT
A:-Propranolol
B:-Propylthiouracil
C:-Carbimazole
D:-Amiodarone
Correct Answer:- Option-C
Question37:-Diuretic with anti remodelling action
A:-Furosemide
B:-Hydrochlorothiazide
C:-Amiloride
D:-Spironolactone
Correct Answer:- Option-D
Question38:-Mu receptor is responsible for all the following effects EXCEPT
A:-Miosis
B:-Bronchodilation
C:-Euphoria
D:-Hypothermia
Correct Answer:- Option-B
Question39:-Most cardiotoxic local anaesthetic is
A:-Procaine
B:-Prilocaine
C:-Bupivacaine
D:-Tetracaine
Correct Answer:- Option-C
Question40:-A normal distribution curve depends on
A:-Mean and sample size
B:-Mean and median
C:-Range and sample size
D:-Mean and standard deviation
Correct Answer:- Option-D
Question41:-SSRI useful in the treatment of premature ejaculation
A:-Dapoxetine
B:-Duloxetine
C:-Venlafaxine
D:-Sertraline
Correct Answer:- Option-A
Question42:-In a clinical trial, comparison of efficacy of a new drug with an existing drug is done in
A:-Phase I
B:-Phase II
C:-Phase III
D:-Phase IV
Correct Answer:- Option-C
Question43:-All of the following are short acting insulin analogs except
A:-Insulin lispro
B:-Insulin aspart
C:-Insulin glargine
D:-Insulin glulisine
Correct Answer:- Option-C
Question44:-Etravirine is
A:-Nucleoside reverse transcriptase inhibitor
B:-Non nucleoside reverse transcriptase inhibitor
C:-Integrase inhibitor
D:-Entry inhibitor
Correct Answer:- Option-B
Question45:-Physiological salt solution used for mammalian smooth muscle experiments
A:-Tyrode solution
B:-Frog ringer solution
C:-De Jalon solution
D:-Mc even solution
Correct Answer:- Option-A
Question46:-Drug most likely to cause malignant hyperthermia is
A:-Propofol
B:-Ketamine
C:-Halothane
D:-Thiopentone sodium
Correct Answer:- Option-C
Question47:-Squalene epoxidase inhibitor is
A:-Terbinafine
B:-Griseofulvin
C:-Miconazole
D:-Tolnaftate
Correct Answer:- Option-A
Question48:-Penicillin G is the drug of choice in
A:-Rickettsial infection
B:-Leptospirosis
C:-Typhoid
D:-Bacterial dysentery
Correct Answer:- Option-B
Question49:-cAMP is the second messenger for the following receptors except
A:-Histamine
B:-Adrenergic
C:-Serotonin
D:-Dopamin
Correct Answer:- Option-C
Question50:-Glucocorticoid with the least mineralocorticoid activity is
A:-Deflazacort
B:-Prednisolone
C:-Methylprednisolone
D:-Hydrocortisone
Correct Answer:- Option-A
Question51:-Macrolide which achieves extensive tissue distribution is
A:-Azithromycin
B:-Roxithromycin
C:-Clarithromycin
D:-Erythromycin
Correct Answer:- Option-A
Question52:-Choose the wrong statement about metronidazole
A:-Preferred drug in intestinal amoebiasis
B:-Highly useful in anaerobic infections
C:-Can product disulfiram like reaction with alcohol
D:-Drug of choice for eradicating amoebic cysts from colon
Correct Answer:- Option-D
Question53:-Docetaxel acts on the following cell cycle phase
A:-S phase
B:-G1 phase
C:-M phase
D:-G2 phase
Correct Answer:- Option-C
Question54:-Gum hypertrophy is caused by all these drugs except
A:-Phenytoin
B:-Verapamil
C:-Nifedipine
D:-Cyclosporine
Correct Answer:- Option-B
Question55:-Drug of choice in digoxin induced ventricular arrhythmia
A:-Propafenone
B:-Lignocaine
C:-Quindine
D:-Procainamide
Correct Answer:- Option-B
Question56:-All are T type calcium channel blockers except
A:-Flunarizine
B:-Ethosuximide
C:-Sodium valproate
D:-Diltiazem
Correct Answer:- Option-D
Question57:-The physical half life of is
A:-8 minutes
B:-8 hours
C:-8 days
D:-8 weeks
Correct Answer:- Option-C
Question58:-The neuromuscular blocking drug that can be used safety in patients with renal and hepatic dyA:-Atracurium
B:-Mivacurium
C:-Pancuronium
D:-Rocuronium
Correct Answer:- Option-A
Question59:-The 5-alpha reductase inhibitor effective in the treatment of male pattern baldness
A:-Flutamide
B:-Finasteride
C:-Bicalutamide
D:-Tadalafil
Correct Answer:- Option-B
Question60:-All of the following drugs are used in hypertensive emergencies except
A:-sodium nitroprusside
B:-Losartan
C:-Labetalol
D:-Esmolol
Correct Answer:- Option-B
Question61:-Inverse agonist of benzodiazepine receptor is
A:-Flumazenil
B:-Gabapentin
C:-Beta carboline
D:-Zopiclone
Correct Answer:- Option-C
Question62:-All are properties of digoxin except
A:-Low steady margin
B:-High volume of distribution
C:-inhibits Na+K+ATPase
D:-Metabolized in liver
Correct Answer:- Option-D
Question63:-Febuxostate is
A:-Non purine inhibitor of xanthine oxidase
B:-Used in acute gout
C:-Uricosuric drug
D:-Given intravenously
Correct Answer:- Option-A
Question64:-The drug with the least oral bioavailability among the following
A:-Ampicillin
B:-Gentamicin
C:-Doxycycline
D:-Ciprofloxacin
Correct Answer:- Option-B
Question65:-Prostaglandin analog used in the treatment of constipation predominant IBS
A:-Lubiprostone
B:-Alosetron
C:-Prucalopride
D:-Cisapride
Correct Answer:- Option-A
Question66:-A metal chelator which can be used in the treatment of a collagen vascular disease but may pA:-Penicillamine
B:-Desferrioxamine
C:-Dimercaprol
D:-Calcium disodium edetate
Correct Answer:- Option-A
Question67:-Neurokinin receptor antagonist used in the treatment of chemotherapy induced vomitting
A:-Dronabinol
B:-Ondansetron
C:-Aprepitant
D:-Rimonabant
Correct Answer:- Option-C
Question68:-All are pharmacogenetically mediated reactions except
A:-Adenosine deaminase deficiency
B:-Succinylcholine apnoea
C:-Coumarin insensitivity
D:-G6PD deficiency
Correct Answer:- Option-A
Question69:-Which one of the following antimicrobial agent has got a ketolide structure
A:-Linezolid
B:-Streptogramins
C:-Aztreonam
D:-Telithromycin
Correct Answer:- Option-D
Question70:-Preferred drug for the treatment of pneumocystis Jiroveci Pneumonia
A:-Erythromycin
B:-Co-trimoxazole
C:-Doxycycline
D:-Clindamycin
Correct Answer:- Option-B
Question71:-Which of the following general anaesthetic has poor muscle relaxant action?
A:-Ether
B:-Nitrous oxide
C:-Halothane
D:-Ketamine
Correct Answer:- Option-B
Question72:-The dose limiting toxicity of doxorubicin is
A:-Hepatic centrilobular necrosis
B:-Congestive cardiac failure
C:-Proximal tubular necrosis
D:-Peripheral neuropathy
Correct Answer:- Option-B
Question73:-Characteristic feature of piperacillin is
A:-Acid labile and penicillinase resistant
B:-Acid resistant and penicillinase labile
C:-Acid labile and penicillinase labile
D:-Acid resistant and penicillinase resistant
Correct Answer:- Option-C
Question74:-Cytochrome P450 isoenzyme involved in the metabolism of most of the drugs is
A:-CYP2E1
B:-CYP2D6
C:-CYP3A4
D:-CYP2C19
Correct Answer:- Option-C
Question75:-Antipsychotic with prokinetic action
A:-Levosulpiride
B:-Amisulpride
C:-Loxapine
D:-Pimozide
Correct Answer:- Option-A
Question76:-Centrally acting skeletal muscle relaxant that acts via adrenergic agonism
A:-Tizanidine
B:-Brimonidine
C:-Baclofen
D:-Chlormezanone
Correct Answer:- Option-A
Question77:-Which of the following is a phase 2 reaction?
A:-Oxidation
B:-Acetylation
C:-Hydrolysis
D:-Reduction
Correct Answer:- Option-B
Question78:-All of the following are anti seizure drugs useful for migraine prophylaxis except
A:-Gabapentin
B:-Topiramate
C:-Vigabatrin
D:-Sodium valproate
Correct Answer:- Option-C
Question79:-The following are mixed agonist antagonist except
A:-Pentazocine
B:-Nalbuphine
C:-Fentanyl
D:-Nalorphine
Correct Answer:- Option-C
Question80:-Chlorpromazine has all the following actions in addition to its anti dopaminergic effect except
A:-Anticholinergic action
B:-Antihistaminic action
C:-Alpha adrenergic blocking action
D:-Beta adrenergic blocking action
Correct Answer:- Option-D
Question81:-Valbenazine is
A:-VMAT2 inhibitor
B:-MAO-B inhibitor
C:-COMT inhibitor
D:-MAO-A inhibitor
Correct Answer:- Option-A
Question82:-Concerning streptogramin, which of the following statement is false?
A:-Active against MRSA
B:-Induce cytochrome P450 enzyme
C:-Useful against vancomycin resistant enterococci
D:-Excreted mainly through feces
Correct Answer:- Option-B
Question83:-The minimal alveolar concentration of an inhalational anaesthetic is a measure of its
A:-Potency
B:-Therapeutic index
C:-Diffusibility
D:-Efficacy
Correct Answer:- Option-A
Question84:-First line ACT under NVBDCP for chloroquine resistant falciparum malaria
A:-Artesunate + sulfadoxine + pyrimethamine
B:-Artemether + lumefantrine
C:-Artesunate + mefloquine
D:-Arterolane + piperaquine
Correct Answer:- Option-A
Question85:-About first order kinetics, true statement is
A:-Fixed amount of the drug is eliminated
B:-Clearance remains constant
C:-Half-life increases with dose
D:-Decreased clearance with increase in dose
Correct Answer:- Option-B
Question86:-Antagonism between adrenaline and histamine is
A:-Physical antagonism
B:-Physiological antagonism
C:-Competitive equilibrium antagonism
D:-Competitive non equilibrium antagonism
Correct Answer:- Option-B
Question87:-Which of the following is not associated with hydrochlorothiazide treatment
A:-Hyponatremia
B:-Hypokalemia
C:-Hypocalcemia
D:-Hyperuricemia
Correct Answer:- Option-C
Question88:-Aminoglycosides are not useful in the treatment of infections with
A:-Pseudomonas
B:-E Coli
C:-Klebsiella
D:-Clostridium difficile
Correct Answer:- Option-D
Question89:-Drug preferred in the treatment of swine flu
A:-Abacavir
B:-Oseltamivir
C:-Acyclovir
D:-Tenofovir
Correct Answer:- Option-B
Question90:-The name of ahlquist is associated with
A:-Classification of cholinergic receptors
B:-Classification of adrenergic receptors
C:-Classification of histamine receptors
D:-Classification of serotonin receptors
Correct Answer:- Option-B
Question91:-All of the following are disease modifying anti-rheumatoid drugs except
A:-Etanercept
B:-Anakinra
C:-Infliximab
D:-Cetuximab
Correct Answer:- Option-D
Question92:-Glycoprotein IIb/IIIa receptor antagonist is
A:-Prasugrel
B:-Ticlopidine
C:-Tirofiban
D:-Cangrelor
Correct Answer:- Option-C
Question93:-Preferred drug in the treatment of drug induced parkinsonism
A:-Levodopa
B:-Selegiline
C:-Trihexyphenidyl
D:-Tolcapone
Correct Answer:- Option-C
Question94:-Stimulation of which receptor will release renin?
A:-Alpha 1
B:-Alpha 2
C:-Beta 1
D:-Beta 2
Correct Answer:- Option-C
Question95:-Evolocumab is used in
A:-Hyperlipidemia
B:-Bronchial asthma
C:-Migraine
D:-Breast cancer
Correct Answer:- Option-A
Question96:-5-HT1A partial agonist among the following
A:-Ketanserin
B:-Hydroxyzine
C:-Cyproheptadine
D:-Buspirone
Correct Answer:- Option-D
Question97:-All of the following can be used as local anaesthetics except
A:-Dexmedetomidine
B:-Centbucridine
C:-Diphenhydramine
D:-Benzyl alcohol
Correct Answer:- Option-A
Question98:-All of the following drugs are included under RNTCP for the treatment of XDR-TB except
A:-Capreomycin
B:-Levofloxacin
C:-Clofazimine
D:-Linezolid
Correct Answer:- Option-B
Question99:-Denosumab is used for the treatment of
A:-Rheumatoid arthritis
B:-Osteoarthritis
C:-Osteoporosis
D:-Systematic lupus erythematosus
Correct Answer:- Option-C
Question100:-Anthelmintic agent with immunomodulatory action
A:-Albendazole
B:-Pyrantel pamoate
C:-Piperazine
D:-Levamisole
Correct Answer:- Option-D