LECTURER IN BIOCHEMISTRY -COLLEGIATE EDUCATION

PROVISIONAL ANSWER KEY
Question Paper Code: 6/2018/OL
Category Code: 245/2017
Exam: Lecturer in Biochemistry
Medium of Question: English
Date of Test 06-02-2018
Department Collegiate Education
Alphacode A
Question1:-Name the monthly brought out by the Publication Division, Government of India, that carries messages of
economic development
A:-Kurukshetra
B:-Yojana
C:-Rosgar Samachar
D:-Ajit
Correct Answer:- Option-B
Question2:-Which of the following is the largest circulated newspaper in India?
A:-Malayala Manorama
B:-Dainik Jagran
C:-Eenadu
D:-Dainik Bhaskar
Correct Answer:- Option-B
Question3:-What are bots?
A:-Robots which manage complex security and surveillance tasks
B:-Remote sensing earth stations of the satellite
C:-Computer programmes designed to work automatically over the internet
D:-Massive virtual storage of information of big corporations
Correct Answer:- Option-C
Question4:-Who among the following is the leader of the Indian National Congress in the 16th Lok Sabha?
A:-Mallikarjun Kharge
B:-Rahul Gandhi
C:-Sonia Gandhi
D:-Gulab Nabi Azad
Correct Answer:- Option-A
Question5:-Post truth which means debates are framed largely by appeals to emotions disconnected from the details of the
issues became widespread during the campaigns of the
A:-2016 Presidential election in the US
B:-2014 Lok Sabha election in India
C:-2012 Presidential election in the US
D:-2012 Russian presidential election
Correct Answer:- Option-A
Question6:-The first Educational magazine in Kerala published by CMS college is
A:-Njana Nikshepam
B:-Vidya Vinodini
C:-Vivekodayam
D:-Vidyasangraham
Correct Answer:- Option-D
Question7:-Kannerum Kinavum is an autobiography of
A:-Sahodaran Ayyappan
B:-V.T. Bhattathirippad
C:-Ayyankali
D:-Kumara Guru
Correct Answer:- Option-B
Question8:-The proprietor and promoter of Swadeshabhimani was
A:-K. Ramakrishna Pilla
B:-A. Balakrishna Pilla
C:-Vakkam Abdul Khader Moulavi
D:-K.P. Kesava Menon
Correct Answer:- Option-C
Question9:-Name the first woman judge of a High Court in India
A:-Anna Chandy
B:-Arya Pallam
C:-Akkamma Cherian
D:-A.V. Kuttimalu Amma
Correct Answer:- Option-A
Question10:-Nivarthana movement in the early 1930s was an agitation demanding adequate representation in the
legislature for
A:-Ezhavas
B:-Muslims
C:-Christians
D:-All of the above
Correct Answer:- Option-D
Question11:-The students are mostly influenced by
A:-Father
B:-Mother
C:-Teacher
D:-Friends
Correct Answer:- Option-C
Question12:-Which is to be considered while constructing curriculum?
A:-Objectives
B:-Values
C:-Methods
D:-Students
Correct Answer:- Option-A
Question13:-A teacher should have knowledge about
A:-Child psychology
B:-Educational psychology
C:-Educational sociology
D:-All these
Correct Answer:- Option-A
Question14:-The method which is also known as laboratory method
A:-Project method
B:-Problem solving method
C:-Heuristic method
D:-Source method
Correct Answer:- Option-D
Question15:-The book ‘Democracy and Education’ is written by
A:-Plato
B:-Aristotle
C:-Dewey
D:-Rousseau
Correct Answer:- Option-C
Question16:-Purposive sampling is also known as
A:-Deliberate sampling
B:-Quota sampling
C:-Simple random sampling
D:-Stratified random sampling
Correct Answer:- Option-A
Question17:-H-test is also known as
A:-Distribution-free test
B:-Fisher Irwin test
C:-Kruskal-Wallis test
D:-Wilcoxon-Manny-Whitney test
Correct Answer:- Option-C
Question18:-The researcher has no control over the variables in
A:-Descriptive Research
B:-Conceptual Research
C:-Fundamental Research
D:-Qualitative Research
Correct Answer:- Option-A
Question19:-Which is not a code of ethics to be followed by a researcher?
A:-Objectivity in data collection
B:-Objectivity in statistical techniques
C:-Objectivity in analysis
D:-Objectivity in findings
Correct Answer:- Option-C
Question20:-The study of commonsense knowledge
A:-Ethnography
B:-Ethnomethodology
C:-Epistemology
D:-Historiography
Correct Answer:- Option-B
Question21:-The Preamble to the Constitution of India was adopted by the Constituent Assembly on
A:-26th November 1949
B:-26th January 1949
C:-26th January 1950
D:-15th August 1947
Correct Answer:- Option-A
Question22:-Which among the following statement/s is/are true about Directive Principles of States Policy?
A:-The provisions contained in this part shall not be enforceable by any court
B:-They are fundamental in the governance of the country
C:-It shall be the duty of the State to apply these principles in making laws
D:-All the above
Correct Answer:- Option-D
Question23:-The President of India takes the oath in the presence of who among the following?
A:-Prime Minister of India
B:-Chief Justice of India
C:-Speaker of Rajya Sabha
D:-Speaker of Lok Sabha
Correct Answer:- Option-B
Question24:-The relations between the Union and the States are provided in which part of the constitution?
A:-Part XI
B:-Part XII
C:-Part XIII
D:-Part XIV
Correct Answer:- Option-A
Question25:-Which article of the Indian Constitution provides provision as to financial emergency?
A:-356
B:-359
C:-368
D:-360
Correct Answer:- Option-D
Question26:-The Right to Information Act was enacted by the Indian Parliament in which year?
A:-2002
B:-2005
C:-2015
D:-None of the above
Correct Answer:- Option-B
Question27:-An Act to give effect to the United Nations Convention on the Rights of Persons with Disabilities was passed by
Parliament in which year?
A:-1995
B:-2000
C:-2016
D:-None of the above
Correct Answer:- Option-C
Question28:-How many guaranteed wage employments per financial year were originally guaranteed by the Mahatma
Gandhi National Rural Employment Act, 2005?
A:-365
B:-180
C:-100
D:-90
Correct Answer:- Option-C
Question29:-As per the National Food Security Act of 2013, who among the following is the head of the household for the
purpose of issue of ration cards?
A:-Oldest male member above the age of 18 years
B:-Oldest female member above the age of 18 years
C:-Oldest member above the age of 18 years
D:-Any member proposed by the family
Correct Answer:- Option-B
Question30:-Which among the following ISO family of standards provide practical tools for companies and organisations to
manage their Environmental responsibilities?
A:-ISO 14000
B:-ISO 9001
C:-ISO 26000
D:-ISO 50001
Correct Answer:- Option-A
Question31:-Fatty acids occurring in humans most commonly
A:-are highly branched structure
B:-have double bonds present in trans configuration
C:-contain an even number of carbon atoms
D:-are limited to 16 or fewer carbon atoms
Correct Answer:- Option-C
Question32:-The active site of all serine proteases contain
A:-Histidine
B:-Asparagine
C:-`gamma`-carboxyglutamate
D:-Lysine or arginine
Correct Answer:- Option-A
Question33:-If a polypeptide has 400 amino acid residues, what is its approximate mass?
A:-22,000 daltons
B:-40,000 daltons
C:-44,000 daltons
D:-80,000 daltons
Correct Answer:- Option-C
Question34:-Gamma(`gamma`)-carboxyglutamate, a derived amino acid is found in
A:-elastin
B:-collagen
C:-hemoglobin
D:-prothrombin
Correct Answer:- Option-D
Question35:-Determine the Km value of the following enzyme catalyzed reaction
(where
`k_1 = 10^9 M^{-1} S^{-1}, k_2 = 10^5 S^{-1}, k_3=10^2 S^{-1}, k_4=10^7 M^{-1} S^{-1}`)
A:-`”10^{-3}”M`
B:-`”10^{-4}”M`
C:-`”10^{-7}”M`
D:-`”10^{-9}”M`
Correct Answer:- Option-B
Question36:-Which of the following contains a hexahydroxy alcohol?
A:-Gangliosides
B:-Phosphatidylcholines
C:-Phosphatidylinositols
D:-Sphingomyelins
Correct Answer:- Option-C
Question37:-The amide nitrogen of glutamine
A:-represents a nontoxic transport form of ammonia
B:-is used in synthesis of asparagine, purines and pyrimidines
C:-can be recovered as ammonia by the action of glutaminase
D:-all of the above
Correct Answer:- Option-D
Question38:-Artificial sweeteners sugar free and equal contain aspartame. Name the two amino acids that are components
of aspartame
A:-Aspartic acid and phenylalanine
B:-Arginine and tyrosine
C:-Aspartic acid and tryptophan
D:-Aspartic acid and glutamic acid
Correct Answer:- Option-A
Question39:-Amino acids present in glutathione include
A:-Glutamate, cysteine, glycine
B:-Aspartate, cysteine, glycine
C:-Glutamate, cysteine, lysine
D:-Glutamate, methionine, glycine
Correct Answer:- Option-A
Question40:-Molar concentration of `”H_2O”` in pure water is
A:-30.5 M
B:-55.5 M
C:-75 M
D:-100 M
Correct Answer:- Option-B
Question41:-Lactate dehydrogenase reaction is monitored by formation of NADH at wavelength
A:-260
B:-280
C:-340
D:-420
Correct Answer:- Option-C
Question42:-Hyaluronate, an important component of vitreous humor and synovial fluid, is
A:-A sugar alcohol
B:-A glycosaminoglycan
C:-A glycoprotein
D:-A glycol lipid
Correct Answer:- Option-B
Question43:-Statins are routinely used for treatment of hypercholesterolemia. They mediate their action by inhibiting
A:-AMP-activated protein kinase
B:-Lecithin-cholesterol acyl transferase
C:-Prostaglandin synthase
D:-Hydroxyl methyl glutaryl CoA reductase
Correct Answer:- Option-D
Question44:-In presence of competitive inhibitor in enzyme catalysed reactions
A:-Vmax increases
B:-Vmax decreases
C:-Km increases
D:-Km decreases
Correct Answer:- Option-C
Question45:-A peptide has a sequence Glu-His-Trp-Ser-Gly-Leu-Lys-Pro-Gly. What is the net charge on the molecule at pH 11?
A:-+2
B:–1
C:-0
D:–2
Correct Answer:- Option-D
Question46:-The alpha carboxyl group of all the 20 standard amino acids have pK value in the range
A:-1.8 – 2.9
B:-4.2 – 6.5
C:-7.2 – 8.2
D:-8.8 – 10.8
Correct Answer:- Option-A
Question47:-IL-2 secretion induces
A:-T-cell proliferation
B:-Vasculature formation
C:-Antiviral activity
D:-MHC-1 expression
Correct Answer:- Option-A
Question48:-Which of the following is used as homology and similarity tool?
A:-EMBOSS
B:-RAMSOL
C:-BLAST
D:-PROSPECT
Correct Answer:- Option-C
Question49:-Abzymes are
A:-Proenzymes
B:-Enzymes that hydrolyse antibiotics
C:-Enzymes present in biodetergents
D:-Antibodies having catalytic activities
Correct Answer:- Option-D
Question50:-Triple stranded collagen helix is stabilized by
A:-Leucine and isoleucine
B:-Proline and hydroxyproline
C:-Phenylalanine and valine
D:-Methionine and cysteine
Correct Answer:- Option-B
Question51:-Which of the following is a DNA binding motif?
A:-helix-loop-helix
B:-leucine zipper
C:-zinc finger
D:-all of the above
Correct Answer:- Option-C
Question52:-The ideal instrument used for getting accurate mass data in peptide mass finger printing is
A:-Electrophoretic apparatus
B:-MALDI-TOF MS instrument
C:-Spectrophotometer
D:-Ultracentrifuge
Correct Answer:- Option-B
Question53:-Which of the following is tumor suppressor gene?
A:-WT1
B:-Src
C:-Myc
D:-None of these
Correct Answer:- Option-A
Question54:-Which organelle is involved in the oxidation of very long-chain fatty acids?
A:-Peroxisomes
B:-Nucleus
C:-Endoplasmic reticulum
D:-Golgi apparatus
Correct Answer:- Option-A
Question55:-Hyper secretion of ACTH is associated with
A:-Amenorrhoea
B:-Cushing’s disease
C:-Steatorrea
D:-Zollinger-Ellison syndrome
Correct Answer:- Option-B
Question56:-Visualization of distribution of transmembrane protein in the plane of a cell membrane can be done in best way
by using
A:-Phase contrast microscope
B:-Freeze fracture electron microscopy
C:-Scanning electron microscopy
D:-Affinity chromatography
Correct Answer:- Option-B
Question57:-Ziehl Neelsen staining procedure is applied for staining
A:-Mycobacterium
B:-Shigella spp.
C:-E. coli
D:-Candida spp.
Correct Answer:- Option-A
Question58:-Which of the following is not a gluconeogenic enzyme?
A:-Phosphoenolpyruvate carboxykinase
B:-Fructose 1,6-bisphosphatase
C:-Glucose 6-phosphatase
D:-Phosphoglucomutase
Correct Answer:- Option-D
Question59:-Which of the following antitumor agents works by impairing de novo purine synthesis?
A:-Acyclovir
B:-5-Fluorouracil
C:-Methotrexate
D:-Hydroxyurea
Correct Answer:- Option-C
Question60:-Which of the following is a method for assessing genome complexity?
A:-Annealing
B:-Electrophoresis
C:-Equilibrium centrifugation
D:- `”C_0t”` curves
Correct Answer:- Option-D
Question61:-The direct effect of cAMP in the protein kinase A pathway is to
A:-activate adenylate cyclase
B:-dissociate regulatory subunits from protein kinase
C:-phosphorylate certain cellular proteins
D:-phosphorylate proteins kinase A
Correct Answer:- Option-B
Question62:-Gamma glutamyl transferase is commonly used marker for diagnosis of
A:-Cardiac diseases
B:-Diabetes
C:-Alzheimer disease
D:-Liver diseases
Correct Answer:- Option-D
Question63:-The histamine is responsible for causing
A:-Vasodilation
B:-Increased capillary permeability
C:-Broncho constriction
D:-All of the above
Correct Answer:- Option-D
Question64:-Which of the following pairs of vectors and DNA insert sizes is correctly matched?
A:-Plasmids 5-10 kb
B:-Cosmids 15 kb
C:-YACs 5000 kb
D:-Bacteriophage lambda 45 kb
Correct Answer:- Option-A
Question65:-How many high-energy bonds are used in the formation of one peptide bond?
A:-1
B:-2
C:-3
D:-4
Correct Answer:- Option-D
Question66:-DNA polymerase III lacks following activities
A:-5 – 3′ polymerase
B:-3 – 5′ exonuclease
C:-5 – 3′ exonuclease
D:-All of the above
Correct Answer:- Option-C
Question67:-Triskelion structure is associated with
A:-Glycophorin A
B:-Clathrin
C:-Elastases
D:-Nucleosomes
Correct Answer:- Option-B
Question68:-The size of Okazaki segments synthesized on lagging strand of bacterial DNA is approximately
A:-100 – 200 nucleotides
B:-100 – 200 base pairs
C:-1000 – 2000 nucleotides
D:-1000 – 2000 base pairs
Correct Answer:- Option-C
Question69:-Galactosemia
A:-is a genetic deficiency of a uridylyltransferase that exchanges galactose 1-phosphate for glucose on UDP-glucose
B:-results from a deficiency of an epimerase
C:-is not apparent at birth but symptoms develop in later life
D:-is an inability to form galactose 1-phosphate
Correct Answer:- Option-A
Question70:-Which of the following consensus sequence is present at -35 position of a typical bacterial promoter?
A:-TTGACA
B:-TATAAT
C:-GAATTC
D:-None of the above
Correct Answer:- Option-A
Question71:-Alfred Hershey and Martha Chase during their experiment on phase DNA used following radioisotopes for
labeling
A:-`”^3H”` and `”^{15}N”`
B:-`”^{14}C”` and `”^{131}I”`
C:-`”^{32}P”` and `”^{35}S”`
D:-`”^3H”` and `”^{60}Co”`
Correct Answer:- Option-C
Question72:-Pentaglycine chain bridges the lysine E-amino group and the D-alanine carboxylic group in the cell wall of
A:-Gram positive bacteria
B:-Gram negative bacteria
C:-Fungi
D:-Higher plants
Correct Answer:- Option-A
Question73:-Lactate to pyruvate conversion takes place in
A:-Muscle
B:-Liver
C:-Muscle and liver
D:-None of these
Correct Answer:- Option-B
Question74:-Attenuational control of gene expression occurs in
A:-Bacteria
B:-Mitochondria
C:-Chloroplasts
D:-All of the above
Correct Answer:- Option-D
Question75:-Which of the following RNA types is comparatively least stable in bacteria?
A:-mRNA
B:-tRNA
C:-rRNA
D:-All are equally stable
Correct Answer:- Option-A
Question76:-The proteins that redistribute lipids across the membrane belong to the class
A:-Flippases
B:-Floppases
C:-Scramblasses
D:-All of the above
Correct Answer:- Option-D
Question77:-Selenocysteine is coded by
A:-AUG
B:-UAA
C:-UAG
D:-UGA
Correct Answer:- Option-D
Question78:-Predict the order of emergence of the following proteins when a mixture of four is chromatographed on a gel
exclusion column at pH 7
Protein 1 ; Mr 6,000 pI = 5
Protein 2 ; Mr 23,000 pI = 8
Protein 3 ; Mr 55,000 pI = 4
Protein 4 ; Mr 10,000 pI = 10
A:-Protein 1, Protein 2, Protein 3, Protein 4
B:-Protein 3, Protein 2, Protein 4, Protein 1
C:-Protein 4, Protein 2, Protein 1, Protein 3
D:-Protein 3, Protein 1, Protein 2, Protein 4
Correct Answer:- Option-B
Question79:-Which of the following is anion exchange resin?
A:-CM cellulose
B:-Dowex-50
C:-DEAE cellulose
D:-CM sepharose
Correct Answer:- Option-C
Question80:-How many bands will appear when hemoglobin is electrophoresed on SDS PAGE in reducing condition?
A:-1
B:-2
C:-3
D:-4
Correct Answer:- Option-B
Question81:-Major emission band during measurement of sodium concentration by flame emission spectroscopy is obtained
at the wave length
A:-589 nm
B:-671 nm
C:-786 nm
D:-852 nm
Correct Answer:- Option-A
Question82:-Identify the commonly used mobile phase in GC-MS.
A:-`”CH_3CN”`
B:-`”H_2O”`
C:-He
D:-`”CO_2″`
Correct Answer:- Option-C
Question83:-For studying protein dynamics in live cells fluorescence recovery after photobleaching (FRAP) is used. It is
based on
A:-Rapid image acquisition of live cells
B:-Mobility of particular fusion protein
C:-Reversible photobleaching of fluorescent protein
D:-Irreversible photobleaching of fluorescent protein
Correct Answer:- Option-B
Question84:-Which combination of ligand and target molecule is wrongly written about affinity chromatography?
A:-Antibody-antigen
B:-Hormone-receptor
C:-Avidin-biotin
D:-Lectin-immunoglobulin
Correct Answer:- Option-D
Question85:-Which of the following dye is used for staining denatured linear RNA during electrophoresis?
A:-Ethydium bromide
B:-Bromophenol blue
C:-Commassie brilliant blue
D:-Acridine orange
Correct Answer:- Option-D
Question86:-Fundamental vibrational motions are studied in
A:-IR spectroscopy
B:-UV-Vis spectroscopy
C:-Circular dichroism
D:-Mass spectrometry
Correct Answer:- Option-A
Question87:-Diapedesis is
A:-An increase in diameter of blood vessels
B:-An increase in capillary permeability
C:-Emigration of phagocytes through the gap between endothelial cells to inflammation site
D:-Adherence of cells to the endothelial wall
Correct Answer:- Option-C
Question88:-Half life of `”^{14}C”` is about 5760 years. After how many years will you get about 3% of the original
activity?
A:-5760 years
B:-17280 years
C:-28800 years
D:-34560 years
Correct Answer:- Option-C
Question89:-The separation of plasma proteins by electrophoresis is commonly carried out at pH
A:-10.0
B:-8.6
C:-7.4
D:-6.5
Correct Answer:- Option-B
Question90:-Which of the following does not participate in antioxidant defense system?
A:-SOD
B:-Catalase
C:-Glutathione
D:-Glucokinase
Correct Answer:- Option-D
Question91:-The enzyme present in Indian cobra venom, responsible for mediating toxic effect, is
A:-Proteinases
B:-Nucleases
C:-Phospholipase
D:-Carbohydrases
Correct Answer:- Option-C
Question92:-Telomerase
A:-is a ribonucleoprotein
B:-is a RNA dependent DNA polymerase
C:-uses 3′ end of DNA as primer and adds successive TTAGGG repeats to it
D:-all of the above
Correct Answer:- Option-D
Question93:-Diisopropylphosphofluoridate is an irreversible inhibitor of the enzyme
A:-Acetylcholinesterase
B:-Glycopeptide transpeptidase
C:-Cytochrome oxidase
D:-Succinate dehydrogenase
Correct Answer:- Option-A
Question94:-Reverse transcriptase has
A:-RNA dependent DNA polymerase activity
B:-DNA dependent DNA polymerase activity
C:-RNase H activity
D:-All of the above
Correct Answer:- Option-D
Question95:-Which of the following is lacking in muscle, but present in normal liver?
A:-Glycogen phosphorylase
B:-Glucose-6-phosphatase
C:-Phosphoglucomutase
D:-Phosphoglucokinase
Correct Answer:- Option-B
Question96:-Full form of DPT vaccine is
A:-Diphtheria, Pertusis, Tetanus
B:-Diphtheria, Pertusis, Typhoid
C:-Diphtheria, Pneumonia, Tetanus
D:-Dysentry, Polio, Tetanus
Correct Answer:- Option-A
Question97:-Penicillin inhibits bacterial growth by irreversibly inactivating the enzyme
A:-Fatty acid synthase
B:-Glycopeptide transpeptidase
C:-Cytochrome oxidase
D:-Hexokinase
Correct Answer:- Option-B
Question98:-Which statistical test is used for comparison of two means from independent samples?
A:-F-test
B:-t-test
C:-Chi-square test
D:-Z-test
Correct Answer:- Option-B
Question99:-Which of the following acts like detergent?
A:-Isoprene
B:-Phospholipids
C:-Deoxycholic acid
D:-Estradiols
Correct Answer:- Option-C
Question100:-Splicing of GU-AG intron
A:-Involves transesterification reaction
B:-Form Y-shaped branch structure
C:-Occurs in prokaryotic messenger RNA
D:-Requires maturase activity
Correct Answer:- Option-A