SENIOR LECTURER IN TUBERCULOSIS AND RESPIRATORY MEDICINE- PULMONARY MEDICINE- MEDICAL EDUCATION

PROVISIONAL ANSWER KEY
Question Paper Code: 17/2018/OL
Category Code: 200/2017
Exam: Senior Lecturer in Tuberculosis and Respiratory
Medicine(Pulmonary Medicine)
Medium of Question: English
Date of Test 15-03-2018
Department Medical Education
Alphacode A
Question1:-Which of the following river is known as ‘Sorrow of Bengal’ ?
A:-Ganga
B:-Damodar
C:-Brahmaputra
D:-Yamuna
Correct Answer:- Option-B
Question2:-The best indicator of economic development of any country is
A:-Per capita income
B:-Agriculture
C:-Transport
D:-Gross production
Correct Answer:- Option-A
Question3:-Sumita Sanyal was associated with which field ?
A:-Politics
B:-Sports
C:-Science
D:-Film Industry
Correct Answer:- Option-D
Question4:-The headquarters of UNESCO
A:-Paris
B:-New York
C:-Rome
D:-Geneva
Correct Answer:- Option-A
Question5:-Year of Poona Pact
A:-1919
B:-1929
C:-1932
D:-1942
Correct Answer:- Option-C
Question6:-Founder of Sadhujana Paripalana Sangham
A:-Sree Narayana Guru
B:-Pandit Karuppan
C:-Ayyankali
D:-Thycaud Ayya
Correct Answer:- Option-C
Question7:-What is the full form of NCERT ?
A:-National Council for Educational Resources and Teaching
B:-National Council of Employees Remedial Teaching
C:-National Council of Educational Research and Training
D:-National Council for Employees Research and Training
Correct Answer:- Option-C
Question8:-The `18^(th)` anniversary of Kargil Vijay Diwas has celebrated on which day in India ?
A:-2017 July 22
B:-2017 June 22
C:-2017 July 26
D:-2017 June 26
Correct Answer:- Option-C
Question9:-Who issued the famous ‘Kundara Proclamation’ ?
A:-Pazhassi Raja
B:-Velu Thampi Dalawa
C:-Marthanda Varma
D:-Paliathachan
Correct Answer:- Option-B
Question10:-‘Jathikummi’ was the famous work of
A:-Dr. Palpu
B:-V. T. Bhattathirippad
C:-Kumaranasan
D:-Pandit Karuppan
Correct Answer:- Option-D
Question11:-Atma Vidya Sangham was founded by
A:-Vagbhatananda
B:-Sahodaran Ayyappan
C:-Velukkutty Arayan
D:-Brahmananda Swami Sivayogi
Correct Answer:- Option-A
Question12:-Temple Entry Proclamation was issued by
A:-Marthanda Varma
B:-Swathithirunnal
C:-Darmaraja
D:-Sree Chithira Thirunal Balarama Varma
Correct Answer:- Option-D
Question13:-In the National Flag which colour is used in the wheel ?
A:-Red
B:-Navy Blue
C:-green
D:-White
Correct Answer:- Option-B
Question14:-First Five Year Plan was started in which year ?
A:-1949
B:-1951
C:-1959
D:-1961
Correct Answer:- Option-B
Question15:-First Regular Indian Censes was conducted in
A:-1889
B:-1888
C:-1881
D:-1880
Correct Answer:- Option-C
Question16:-2017 World Athletic Championship was held at
A:-New York
B:-Russia
C:-Germany
D:-London
Correct Answer:- Option-D
Question17:-Founder of Travancore Muslim Mahajana Sabha
A:-Vakkom Adbul Khadar Moulavi
B:-Khan Abdul Gafferkhan
C:-Sayyed Ahamed Khan
D:-Muhammed Abdu Rahman Saheb
Correct Answer:- Option-A
Question18:-Who was honoured with the title ‘Bharata Kesari’ by the President of India ?
A:-Sree Narayana Guru
B:-Mannathu Padmanabha Pillai
C:-Kumara Guru
D:-Kumaranasan
Correct Answer:- Option-B
Question19:-The famous tourist centre Ajanta is situated at
A:-Gujarat
B:-Goa
C:-Madhya Pradesh
D:-Maharashtra
Correct Answer:- Option-D
Question20:-1857 Revolt was started at
A:-Meerut
B:-Jhansi
C:-Kanpur
D:-Bihar
Correct Answer:- Option-A
Question21:-Alpha 1 anti trypsine deficiency is caused by mutation in the gene
A:-SERPINA1
B:-ACVRL1
C:-SFTPA2
D:-CSF2RA
Correct Answer:- Option-A
Question22:-At the end of a deep breath what percent of lung volume is air ?
A:-60
B:-80
C:-70
D:-90
Correct Answer:- Option-B
Question23:-Fibre types in respiratory muscles that help in sneezing and coughing is
A:-Type I
B:-Type IIa
C:-Type IIb
D:-Type IIx
Correct Answer:- Option-D
Question24:-Most common pattern of ILD in Rheumatoid arthritis is
A:-UIP
B:-COP
C:-NSIP
D:-DIP
Correct Answer:- Option-A
Question25:-Fall in FEV1 in non-smoking adults are at the rate of
A:-15 ml/year
B:-30 ml/year
C:-45ml/year
D:-60ml/year
Correct Answer:- Option-B
Question26:-All are true regarding COPD exacerbations, except
A:-Best predictor of future exacerbations
B:-More common in patients with chronic cough and sputum production
C:-Spirometry during the acute exacerbation is usually helpful in predicting the severity and duration
D:-Many of these eventually resolve without specific treatment
Correct Answer:- Option-C
Question27:-All are causes of exacerbations of asthma, except
A:-Rhino virus
B:-Hemophilus influenza
C:-Chlamydia
D:-Para influenza virus
Correct Answer:- Option-B
Question28:-Anti inflammatory action of theophyllins are mediated through
A:-Phosphodiesterase
B:-Histone deacetylase2
C:-All of the above
D:-None of the above
Correct Answer:- Option-B
Question29:-NSAID well tolerated in Aspirin induced asthma is
A:-Indomethacine
B:-Ketorolac
C:-Piroxicam
D:-Sodium salicylate
Correct Answer:- Option-D
Question30:-Prevalence of exercise induced asthma may be more in the following group
A:-Children
B:-Elite athletes
C:-All of the above
D:-None of the above
Correct Answer:- Option-C
Question31:-The most effective drug in exercise induced asthma is
A:-Beta adrenergic agonists
B:-Chromolin sodium
C:-Theophyllins
D:-Leukotriene antagonists
Correct Answer:- Option-A
Question32:-Pathognomonic of ABPA among the following is
A:-Elevated aspergillus specific IgE
B:-Elevated aspergillus specific IgG
C:-Charcot-Leyden crystals
D:-Hyphae filled mucous plug
Correct Answer:- Option-D
Question33:-Unilateral vocal cord paralysis causes
A:-Variable intrathoracic obstruction
B:-Variable extra thoracic obstruction
C:-Fixed intrathoracic obstruction
D:-Fixed extra thoracic obstruction
Correct Answer:- Option-B
Question34:-Most common type of benign tracheal tumour is
A:-Chondroma
B:-Papilloma
C:-Hemangioma
D:-Hamartoma
Correct Answer:- Option-A
Question35:-All are true in Vocal Cord Dysfunction, except
A:-Stridor/wheeze
B:-Symptoms may remit without treatment
C:-Presence of bronchial hyper responsiveness
D:-Normal alveolar arterial gradient
Correct Answer:- Option-C
Question36:-F508 del mutation in cystic fibrosis results in
A:-Block in processing
B:-Block in regulation
C:-Altered conductance
D:-Reduced synthesis
Correct Answer:- Option-A
Question37:-Risk factors for liver disease in cystic fibrosis are all the following, except
A:-Meconium ileus
B:-PiZ heterozygous state
C:-TGF beta-1 polymorphism
D:-Female sex
Correct Answer:- Option-D
Question38:-Infections with the following organism is associated with development of bronchiectasis.
A:-Streptococcus pneumoniae
B:-Haemophilus influenzae
C:-Staphylococcus aureus
D:-Morexella catarrhalis
Correct Answer:- Option-C
Question39:-Most common form of ILD is
A:-Hypersensitivity pneumonitis
B:-Sarcoidosis
C:-CT-ILD
D:-IPF
Correct Answer:- Option-D
Question40:-Differentiating feature between RB-ILD and DIP is
A:-Age of onset
B:-Involvement of alveoli
C:-Smoking score more than 30 pack years
D:-Golden brown pigments in macrophages
Correct Answer:- Option-B
Question41:-Detergent workers disease is caused by
A:-Cladosporium spp.
B:-Pseudomonas spp.
C:-Aureobasidium spp.
D:-Bacillus subtilis
Correct Answer:- Option-D
Question42:-Shrinking lung syndrome is seen in
A:-SLE
B:-Emphysema
C:-IPF
D:-Scleroderma
Correct Answer:- Option-A
Question43:-All are true regarding Rheumatoid pleural effusion, except
A:-Low sugar
B:-Leukocytosis
C:-pH more than 7.2
D:-Exudative effusion
Correct Answer:- Option-C
Question44:-Radiologic appearance of PLCH include all, except
A:-Mid and lower zone involvement
B:-Ill defined nodules
C:-Cysts of bizarre shape
D:-Pleural thickening
Correct Answer:- Option-A
Question45:-All are true regarding Alveolar microlithiasis, except
A:-Autosomal recessive disorder
B:-Calcium metabolism disorder
C:-Asymptomatic with abnormal CXR
D:-Mutation in Type II b sodium phosphate cotransporter gene
Correct Answer:- Option-B
Question46:-In which year Robert Koch received Nobel Prize for his contribution in the field of Tuberculosis ?
A:-1888
B:-1905
C:-1912
D:-1886
Correct Answer:- Option-B
Question47:-National Tuberculosis programme was started in India in the year
A:-1906
B:-1956
C:-1978
D:-1962
Correct Answer:- Option-D
Question48:-Swimming pool granuloma is caused by
A:-M.marinum
B:-M.ulcerans
C:-M.avium
D:-M.smegmatis
Correct Answer:- Option-A
Question49:-All are solid culture media in Tuberculosis, except
A:-L-J medium
B:-Loeffler serum slope
C:-Middlebrooks medium
D:-Pawlowskys medium
Correct Answer:- Option-C
Question50:-Most common form of skeletal tuberculosis is
A:-Tuberculosis of hip
B:-Tuberculosis of knee joint
C:-Spinal tuberculosis
D:-Tuberculosis of shoulder joint
Correct Answer:- Option-C
Question51:-Which of the following is unusual in Churg stauss syndrome ?
A:-cANCA
B:-Elevated ESR
C:-Elevated CRP
D:-Elevated Eosinophil Count
Correct Answer:- Option-A
Question52:-Which is not true in chylothorax ?
A:-Lymphocyte predominant
B:-Exudate
C:-Elevated LDH
D:-Pleural fluid triglyceride more than 110 mg/dl
Correct Answer:- Option-C
Question53:-Triad of Yellow nail syndrome consists of all, except
A:-Nail changes
B:-Pleural effusion
C:-Bronchiectasis
D:-Lymphedema
Correct Answer:- Option-C
Question54:-Most common lung cancer type associated with pleural involvement
A:-Squamous cell carcinoma
B:-Adenocarcinoma
C:-Large cell carcinoma
D:-Small cell carcinoma
Correct Answer:- Option-B
Question55:-All are true regarding pleural effusion associated with mesothelioma, except
A:-Presence of hyaluronic acid is diagnostic
B:-Low pH
C:-Low sugar
D:-LDH concentration greater than that of carcinoma of pleura
Correct Answer:- Option-A
Question56:-Haller index suggesting significant sternal depression in Pectus excavatum is
A:-2.5
B:-More than 3.25
C:-Less than 3.25
D:-Less than 2.5
Correct Answer:- Option-B
Question57:-Chronic mountain sickness is characterized by all the features, except
A:-Dyspnoea on exertion
B:-Extreme polycythemia
C:-Elevated haematocrit
D:-Pulmonary hypertension
Correct Answer:- Option-A
Question58:-EGFR mutations positive lung cancers have all the following features, except
A:-Exclusively in NSCLC
B:-More in women
C:-More in smokers
D:-20-30% Asian lung cancer patients
Correct Answer:- Option-C
Question59:-Carcinoid syndrome is seen in all, except
A:-Carcinoid tumours
B:-Large cell carcinoma
C:-Squamous cell carcinoma
D:-Small cell carcinoma
Correct Answer:- Option-C
Question60:-Hypercalcemia most frequently occur in
A:-Squamous cell cancer
B:-Adenocarcinoma
C:-Small cell lung cancer
D:-Large cell carcinoma
Correct Answer:- Option-A
Question61:-Spherical pneumonia is associated with
A:-Streptococcal pneumonia
B:-Haemophilus influenza
C:-Coxiella burnetti
D:-All of the above
Correct Answer:- Option-D
Question62:-Which is not true about pneumatoceles ?
A:-Seen in young children
B:-Develop late in the course of pneumonia
C:-Thin walled air filled spaces
D:-Disappear in a few months
Correct Answer:- Option-B
Question63:-Liver function abnormalities and clinical hepatitis in atypical pneumonia usually suggest
A:-Qfever
B:-Mycoplasma pneumonia
C:-Legionella pneumonia
D:-Chlamydia pneumonia
Correct Answer:- Option-A
Question64:-Lemmiere syndrome is caused by
A:-M.abscesus
B:-Peptostreptococcus
C:-Prevotella oralis
D:-F.necrophorum
Correct Answer:- Option-D
Question65:-Important infection in post transplant patients, beyond one month post surgery is
A:-CMV
B:-P. jiroveci
C:-A. fumigates
D:-Nocardia asteroides
Correct Answer:- Option-A
Question66:-Mechanism of action of fluoroquinolones is
A:-Inhibition of protein synthesis
B:-Interfere with DNA gyrase/topoisomerase IV leading to cell wall lysis
C:-LPS mediated increased cell wall permeability to antibiotics
D:-Both (a) and (c)
Correct Answer:- Option-B
Question67:-Most common site for aspiration pneumonia is
A:-Superior segment of RLL
B:-Posterior segment of LUL
C:-Medial segment of RML
D:-Superior segment of LLL
Correct Answer:- Option-A
Question68:-Most likely diagnosis in an edentulous patient presenting with a cavitating lesion in CXR in all, except
A:-Bronchial obstruction
B:-Pulmonary embolus
C:-Septic embolus
D:-Lung abscess
Correct Answer:- Option-D
Question69:-Diagnostic threshold for BAL in nosocomial pneumonia is
A:-`10^(5)` CFU/ml
B:- `10^(3)` CFU/ml
C:-`10^(4) ` CFU/ml
D:-` 10^(6) ` CFU/ml
Correct Answer:- Option-C
Question70:-Which of the following mycobacteriae is not associated with human infection ?
A:-M.africanum
B:-M.canettii
C:-M.bovis BCG
D:-M.caprae
Correct Answer:- Option-D
Question71:-Droplet nuclei are not the mode of transmission among the following diseases
A:-Measles
B:-Tuberculosis
C:-Influenza
D:-Varicella
Correct Answer:- Option-C
Question72:-Most common form of extrapulmonary tuberculosis is
A:-Pleural effusion
B:-Spinal tuberculosis
C:-Genitourinary TB
D:-Lymphnode TB
Correct Answer:- Option-D
Question73:-All are true about Xpert-MTB-RIF, except
A:-Nucleic acid amplification test
B:-Sophisticated laboratory needed, not useful in resource poor settings
C:-Simultaneously detects RIF resistance
D:-Specificity 90-100%
Correct Answer:- Option-B
Question74:-Diagnostic test of choice in pneumocystis jerovecii, is
A:-Diff-Quick stain
B:-Induced sputum with direct immunofluorescent staining
C:-Wright’s stain
D:-Toluidine blue O
Correct Answer:- Option-B
Question75:-Mechanism of Bleomycin lung toxicity include all, except
A:-Generation of oxygen free radicals
B:-Direct effects on DNA
C:-Absence of enzyme Bleomycin hydrolase
D:-Inhibition of enzyme Bleomycin hydrolase
Correct Answer:- Option-D
Question76:-Which is not correct about omalizumab ?
A:-Recombinant humanised antibody
B:-Dose dependent on serum level of IgE alone
C:-Indicated in moderate to severe allergic asthma
D:-Should not be initiated at acute stage of asthma
Correct Answer:- Option-B
Question77:-IRIS can occur in all the following conditions in a patient with HIV, except
A:-Mycobacterium tuberculosis
B:-Leishmaniasis
C:-Fungal infections
D:-Bacterial pneumonia
Correct Answer:- Option-D
Question78:-Permissive hyper capnoea is used in all the following, except
A:-Acute lung injury
B:-Increased intracerebral pressure
C:-ARDS
D:-Neonatal respiratory failure
Correct Answer:- Option-B
Question79:-Oral bio-availability is maximum for which among the following inhaled steroids ?
A:-Fluticasone
B:-Mometasone
C:-Ciclasonide
D:-Beclomethasone
Correct Answer:- Option-D
Question80:-All are features of chronic eosinophilic pneumonia, except
A:-Elevated eosinophil count in blood and BAL
B:-Reverse pulmonary edema pattern in CXR
C:-Male sex predominance
D:-Presence of interstitial fibrosis pathologic hall mark
Correct Answer:- Option-C
Question81:-Chronic pleuritic pain is characteristic in
A:-Lung cancer
B:-Pneumoconiosis
C:-Pulmonary embolism
D:-Mesothelioma
Correct Answer:- Option-D
Question82:-Absolute contraindication for argonplasma coagulation is
A:-Implantable defibrillator
B:-`FiO_(2)` less than 0.4
C:-Major airway bleed
D:-Post infectious airway stenosis
Correct Answer:- Option-A
Question83:-Elevated DLCo in asthma is due to
A:-Associated large lung volume
B:-Increased perfusion of well ventilated upper zones
C:-None of the above
D:-both (1) & (2)
Correct Answer:- Option-D
Question84:-Varenicline helps in smoking cessation by a) Being partial agonist of nicotinic cholinergic receptor b) Blocks
effects of smoke on nicotine receptor c) As a result of receptor blockade nicotine withdrawal symptoms are relieved d)
Desire to smoke is reduced
A:-a, b and c
B:-b, c and d
C:-a, b and d
D:-a, c and d
Correct Answer:- Option-C
Question85:-Which is not true about Pancoast syndrome ?
A:-Most common initial symptom is shoulder pain
B:-Intrinsic muscles of the hand may be involved
C:-Associated with superior sulcus tumour
D:-CT is superior imaging modality
Correct Answer:- Option-D
Question86:-Malignancy commonly associated with airway metastasis is
A:-Prostatic cancer
B:-Colon cancer
C:-Osteogenic sarcoma
D:-Ca. Tongue
Correct Answer:- Option-B
Question87:-Criteria for diagnosing a definite Hereditary Hemorrhagic Telangiectasia include all, except
A:-Recurrent spontaneous nose bleeds
B:-Mucocutaneous telangiectasia
C:-No first degree relative involved
D:-Visceral involvement
Correct Answer:- Option-C
Question88:-Skin manifestation that is specific for sarcoidosis
A:-Erythema nodosum
B:-Lupus pernio
C:-Subcutaneous nodules
D:-Plaques
Correct Answer:- Option-B
Question89:-Not true about Idiopathic Pulmonary Hemosiderosis, from the following is
A:-Predominantly disease of children
B:-Recurrent haemoptysis
C:-Renal involvement is common
D:-Histology of lung shows bland alveolar haemorrhage with hemosiderin accumulation
Correct Answer:- Option-C
Question90:-The commonest type of lung carcinoma seen in women and non-smokers
A:-Adenocarcinoma
B:-Large cell carcinoma
C:-Small cell carcinoma
D:-Squamous cell carcinoma
Correct Answer:- Option-A
Question91:-The commonest malignant tumour seen in asbestos worker
A:-Bronchogenic carcinoma
B:-Gastric carcinoma
C:-Glioblastoma multiforme
D:-Malignant mesothelioma
Correct Answer:- Option-A
Question92:-Cushing syndrome is usually associated with all, except
A:-Carcinoid tumour
B:-Squamous cell carcinoma
C:-Neuroblastoma
D:-Small cell carcinoma
Correct Answer:- Option-B
Question93:-Most common radiological pattern associated with Bronchioloalveolar carcinoma
A:-Multiple nodular lesions
B:-Consolidative pattern
C:-Perihilar opacity with cavitation
D:-Single nodular lesions
Correct Answer:- Option-D
Question94:-The commonest type of emphysema
A:-Irregular
B:-Centriacinar
C:-Panacinar
D:-Paraseptal
Correct Answer:- Option-B
Question95:-The pneumoconiosis which can be seen commonly in tobacco smokers is
A:-Anthrocosis
B:-Byssinosis
C:-Siderosis
D:-Silicosis
Correct Answer:- Option-A
Question96:-The type of pneumoconiosis in which eggshell calcification of hilar lymph nodes is seen in chest X-ray is
A:-Anthracosis
B:-Berylliosis
C:-Coalworkers pneumoconiosis
D:-Silicosis
Correct Answer:- Option-D
Question97:-Bronchial carcinoma can be associated with all except
A:-Acanthosis nigricans
B:-Myesthenia gravis
C:-Hypercalcaemia
D:-SIADH
Correct Answer:- Option-B
Question98:-All are true about asbestosis except
A:-Asteriod bodies are characteristic
B:-Begins in the lower lobe and subpleurally
C:-Marked diffuse pulmonary interstial fibrosis
D:-Pleural plaques most common manifestation
Correct Answer:- Option-A
Question99:-All are true about silicosis except
A:-Most prevalent chronic occupational disease in the world
B:-Quartz is most commonly implicated form
C:-Initial lesions tend to localize in the lower lung zone
D:-There is no known clear association of silica and development of lung cancer
Correct Answer:- Option-C
Question100:-Bedaquiline is not started in MDR TB in all the situations, except
A:-Pyrazinamide and at least 4 second line drugs are not available according to sensitivity tests
B:-Uncontrolled cardiac arrhythmia requiring medication
C:-Prolonged QT interval (more than 450 ms)
D:-Presence of chorioretinitis
Correct Answer:- Option-A